Cover & TOC
Document type
články
články
Document record
Source: BMČ - články
Title
Novel ultra-high-frequency electrocardiogram tool for the description of the ventricular depolarization pattern before and during cardiac resynchronization / P. Jurak, K. Curila, P. Leinveber, FW. Prinzen, I. Viscor, F. Plesinger, R. Smisek, R. Prochazkova, P. Osmancik, J. Halamek, M. Matejkova, J. Lipoldova, M. Novak, R. Panovsky, P. Andrla, V. Vondra, P. Stros, J. Vesela, D. Herman,
Author
Jurák, Pavel
Institute of Scientific Instruments, The Czech Academy of Sciences, Brno, Czech Republic.

Curila, Karol
Department of Cardiology, Cardiocenter, Third Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, Prague, Czech Republic.

Leinveber, Pavel
International Clinical Research Center, St Anne's University Hospital, Brno, Czech Republic. First Department of Internal Medicine-Cardioangiology, Faculty of Medicine of Masaryk University, St Anne's University Hospital, Brno, Czech Republic.

Prinzen, Frits W
Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.

Viscor, Ivo
Institute of Scientific Instruments, The Czech Academy of Sciences, Brno, Czech Republic.

Plesinger, Filip
Institute of Scientific Instruments, The Czech Academy of Sciences, Brno, Czech Republic.

Smisek, Radovan
Institute of Scientific Instruments, The Czech Academy of Sciences, Brno, Czech Republic. Department of Biomedical Engineering, The Faculty of Electrical Engineering and Communication, Brno University of Technology, Brno, Czech Republic.

Prochazkova, Radka
Department of Cardiology, Cardiocenter, Third Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, Prague, Czech Republic.

Osmancik, Pavel
Department of Cardiology, Cardiocenter, Third Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, Prague, Czech Republic.

Halamek, Josef
Institute of Scientific Instruments, The Czech Academy of Sciences, Brno, Czech Republic.

Matejkova, Magdalena
International Clinical Research Center, St Anne's University Hospital, Brno, Czech Republic.

Lipoldová, Jolana
International Clinical Research Center, St Anne's University Hospital, Brno, Czech Republic. First Department of Internal Medicine-Cardioangiology, Faculty of Medicine of Masaryk University, St Anne's University Hospital, Brno, Czech Republic.

Novák, Miroslav
International Clinical Research Center, St Anne's University Hospital, Brno, Czech Republic. First Department of Internal Medicine-Cardioangiology, Faculty of Medicine of Masaryk University, St Anne's University Hospital, Brno, Czech Republic.

Panovský, Roman
International Clinical Research Center, St Anne's University Hospital, Brno, Czech Republic. First Department of Internal Medicine-Cardioangiology, Faculty of Medicine of Masaryk University, St Anne's University Hospital, Brno, Czech Republic.

Andrla, Petr
Institute of Scientific Instruments, The Czech Academy of Sciences, Brno, Czech Republic.

Vondra, Vlastimil
Institute of Scientific Instruments, The Czech Academy of Sciences, Brno, Czech Republic.

Stros, Petr
Department of Cardiology, Cardiocenter, Third Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, Prague, Czech Republic.

Veselá, Jana
Department of Cardiology, Cardiocenter, Third Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, Prague, Czech Republic.

Herman, Dalibor
Department of Cardiology, Cardiocenter, Third Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, Prague, Czech Republic.

Cited source
Journal of cardiovascular electrophysiology. 2020, roč. 31, č. 1, s. 300-307. ISSN: 1045-3873; 1540-8167 (elektronická verze).
Date of issue
2020
Language
angličtina
Country
Spojené státy americké
Document type
články
DOI
Pubmed ID
Link
Record number
bmc20028643
Persistent link
English Abstract
INTRODUCTION: The present study introduces a new ultra-high-frequency 14-lead electrocardiogram technique (UHF-ECG) for mapping ventricular depolarization patterns and calculation of novel dyssynchrony parameters that may improve the selection of patients and application of cardiac resynchronization therapy (CRT). METHODS: Components of the ECG in sixteen frequency bands within the 150 to 1000 Hz range were used to create ventricular depolarization maps. The maximum time difference between the UHF QRS complex centers of mass of leads V1 to V8 was defined as ventricular electrical dyssynchrony (e-DYS), and the duration at 50% of peak voltage amplitude in each lead was defined as the duration of local depolarization (Vd). Proof of principle measurements was performed in seven patients with left (left bundle branch block) and four patients with right bundle branch block (right bundle branch block) before and during CRT using biventricular and His-bundle pacing. RESULTS: The acquired activation maps reflect the activation sequence under the tested conditions. e-DYS decreased considerably more than QRS duration, during both biventricular pacing (-50% vs -8%) and His-bundle pacing (-77% vs -13%). While biventricular pacing slightly increased Vd, His-bundle pacing reduced Vd significantly (+11% vs -36%), indicating the contribution of the fast conduction system. Optimization of biventricular pacing by adjusting VV-interval showed a decrease of e-DYS from 102 to 36 ms with only a small Vd increase and QRS duration decrease. CONCLUSIONS: The UHF-ECG technique provides novel information about electrical activation of the ventricles from a standard ECG electrode setup, potentially improving the selection of patients for CRT and application of CRT.
Clipboard
Further actions
Online access NLK