MeSH Descriptor
Source: MeSH 2021 deskriptory
Main Heading
mikro RNA
English Heading
MicroRNAs
See
miRNA
mikroRNA
stRNA
See
miRNAs [T474061]
Micro RNA [T474062]
MicroRNA [T474063]
miRNA [T474064]
RNA, Small Temporal [T474580]
stRNA [T474581]
Small Temporal RNA [T474582]
Primary MicroRNA [T692414]
Primary miRNA [T692415]
pri-miRNA [T692416]
pre-miRNA [T693250]
Related Descriptors
Preferred Concept
Scope Note
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
Other Concepts
History note
2003; use MICRORNAS (NM) 2001-2002
Public Note
2003; MICRORNAS was indexed under RNA, UNTRANSLATED and RNA, ANTISENSE 2001-2002
Record number
D035683
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